Infectious diseases cause an overwhelming number of deaths around the world and their clinical management is often hampered by the emergence of multidrug-resistant strains. Therefore, prevention through vaccination is currently the best course of action to beat them. A vaccine is a biological agent that provides active acquired immunity to a particular disease. A vaccine usually contains an agent that resembles a disease-causing microorganism. It is often made from killed or weakened forms of the microbe, its toxins or one of its surface proteins. The body’s immune system is stimulated to recognize the agent as a threat and destroy it, and any of these microorganisms that it later encounters. Vaccines can be prophylactic (e.g. to prevent or reduce the impact of a future infection by a pathogen), or therapeutic (e.g. cancer vaccines are being investigated). Vaccines exist in many different forms which may contain the live, attenuated virus, or an inactivated micro-organism, or some unique molecular composition of the organism that causes illnesses. Vaccines can generally be classified as Live Attenuated Vaccine, Inactivated Vaccine, Subunit Vaccine, Vector Vaccine, Conjugate Vaccine, DNA and RNA Vaccine and more. Vaccines
PRODUCT NAME LABEL COMPOSITION PACK THERAPEUTIC USE DTwP – rHeb B – Hib (liquid) Pentavalent : Diphtheria, Tetanus, Pertussis (Whole cell), Hepatitis B (rDNA) and Haemophilus Type b conjugate Vaccine (Adsorbed) WHO Prequalified Each dose of 0.5 ml contains Diphtheria Formol Toxoid : >30 IU (>20 Lf to < 30 Lf) Tetanus Formol Toxoid : > 60 IU (> 5 Lf to < 25 Lf) Bordetella Pertussis (Whole cell, Killed > 4 IU r-HBsAg : (Recombinant HBs antigen produced in Pichia Pastoris) Purified capsular polysaccharide of Hib (PRP) covalently linked to 20 to 36.7 µg of tetanus formol toxoid : 11 µg Al+++ (as AIPO4) : < 1.25 mg Preservative : Thiomersal : 0.5 ml vial 5 ml vial Immunization against Diphtheria, Tetanus, Pertussis and Hepatitis B and Haemophilus Influenza type b DTwP –rHep B + Hib (lyophilized) Pentavalent : Diphtheria, Tetanus, Pertussis (Whole Cell), Hepatitis B (rDNA) and Haemophilus Type b Conjugate Vaccine (Adsorbed) WHO Prequalified Each reconstituted dose of 0.5 ml contains : Diphtheria Toxoid : > 30 IU Tetanus Toxoid : > 60 IU B.Pertussis (Whole cell) : > 4 IU r-HBs Ag : 10 µg Purified Capsular Polysaccharide (PRP): 10 µg Tetanus Toxoid (Carrier protein) 19 to 33 µg Al+++ (as AIPO4) : < 1.25 mg Preservative : Thiomersal BP 0.01% 0.5 ml vial 5 ml vial Immunization against Diphtheria, Tetanus, Pertussis and Hepatitis B and Haemophillus Influenza type b TT Adsorbed Tetanus Vaccine WHO Prequalified Each dose of 0.5 ml contains Tetanus Toxoid : 5 Lf to ≤ 25 Lf Aluminium Phosphate : 1.5 mg Thiomersal : 0.01 % w/v 0.5 ml vial 5 ml vial 10 ml vial Active Immunization for Tetanus JE Japanese Encephalitis Vaccine (Human) (Purified Inactivated Vaccine – Adsorbed) WHO Prequalified Each 0.5 ml contains Purified Inactivated Japanese Encephalitis Virus Strain (SA14-14-2): 6 µg Aluminium as Aluminium Hydroxide : 0.1% w/v Phosphate Buffer Saline q.s 0.5 ml vial 0.25 ml vial Immunization against Japanese Encephalitis DTwP Adsorbed Diphtheria, Tetanus and Pertussis (Whole Cell) Vaccine 0.5 ml dose contains Diphtheria Toxoid : 20 Lf to ≤ 30Lf Tetanus Toxoid : 5 Lf to ≤25 Lf B.Pertussis (Whole cell) : 4 IU Aluminium phosphate : 1.5 mg Thiomersal : 0.01 % w/v 0.5 ml vial 5 ml vial 10 ml vial Immunization for Diphtheria, Pertussis and Tetanus DT Adsorbed Diphtheria and Tetanus Vaccine Each dose of 0.5 ml contains Diphtheria Toxoid : 20 Lf to ≤ 30 Lf Tetanus Toxoid : 5 Lf to ≤ 25 Lf Aluminium Phosphate : 1.5 mg Thiomersal : 0.01 % w/v 0.5 ml vial 5 ml vial 10 ml vial Immunization for Diphtheria and Tetanus Td Adsorbed Diphtheria and Tetanus Vaccine for Adults and Adolescents Each dose of 0.5 ml contains : Diphtheria Toxoid < 2 Lf Tetanus Toxoid >20 IU Adsorbed on Aluminium Phosphate (Al PO4) > 1.5 mg Preservative : Thiomersal 0.01% w/v 0.5 ml vial 5 ml vial Immunization against Tetanus and Diphtheria for Adults and Adolescents